Differential diagnosis The differential diagnosis for a renal cortical defect includes 1,2: renal scarring re. However there is a large filling defect in the left renal pelvis (arrows), suspicious for a neoplasm. Bone scans use an IV tracer that concentrates in areas of high bone . Published . AJR Am J Roentgenol . 2. Right and left renal collecting systems are assessed separately (hence most CTU's will yield results for two renal collecting systems). 4.3.4.3. We tracked immediate complications and tract seeding on follow-up imaging. European Association of Urology. Imaging Key Information. Bhaskar Somani, a consultant urological surgeon at Southampton General Hospital, says the UK is sitting on a kidney stone "timebomb" - Although the body tries to pass stones out of the urinary system, they can lodge in the kidney tube and cause severe abdominal and groin pain which, in many cases, can only be corrected through. Bernstein RG, Siegelman JS, Tein AB, et al: Huge filling defect in the bladder, caused by intravesical enlargement of the prostate . This patient presented with haematuria. Radiolucent filling defect in continuity with the wall of the collecting system Ultrasonography Echogenic focus within the ureter and renal pelvis associated with the moderate to severe hydronephrosis Computed Tomography A ureteral or renal pelvis mass with attenuation in the soft-tissue range of 30-40 Hounsfield units Magnetic Resonance Imaging This is because the contrast material is more opaque than the filling defect. the . A patulous system with decreased peristalsis can result in dilation of the renal collecting system in the absence of a mechanical obstruction in a variety of clinical settings, to include vesicoureteral reflux (VUR), megaureter, and prior mechanical obstruction or infection. Rimlike calcificationof necrotic papilla occurs. Kidney Stone (right kidney obstruction) Delayed CT scan with (1) soft tissue windows and (2) bone windows shows normal excretion of contrast from left kidney (LK) but dilated collecting systemin the right kidney (arrows) with delayed excretion. Urinary tract imaging and pathology . The differential diagnosis of a radiolucent filling defect in the intrarenal collecting system or renal pelvis may include transitional cell carcinoma, blood clot . Diagnostic uncertainty is common, especially where differential diagnoses for filling defects in adults include tumors [9]. Although conferring no radiation to the patient, MRI is a second-line imaging modality in pregnant women because stones are not directly visible on MRI and only seen as a filling defect in the collecting system. The video of the diagnostic flexiureterorenoscopy . Filling defects that are free appear radiolucent when surrounded with positive contrast material. 23-6). mon reason for urinary tract imaging. Using ultrasound alone, it is often difficult to differentiate renal transitional cell carcinoma from other causes of filling defects of the renal collecting system such as blood clots, sloughed papillae, or fungus balls. Percutaneous access may be performed to permit antegrade pyelography. In this case report they described features of papillary necrosis such as sloughed papilla in the calyx, clubbing of the calyx, a golf ball on a tee appearance and filling defects in the major calyx giving rise to a lobster claw appearance. Filling defects in the renal collecting system and the bladder, as seen with IVU, CT, and retrograde pyelography, are present in a number of other pathologies. Filling defect of renal pelvis found on diagnostic imaging. Ductogram 4. They are usually centered on the renal pelvis (rather than the renal parenchyma as is the case with RCC) and range in size from small filling defects (difficult to see without distension or collecting system contrast) to large masses which obliterate the renal sinus fat (TCC is one of the causes of the so-called faceless kidney) 2. Poor visualization of renal collecting system in intravenous urography as an indicator of invasive transitional cell carcinoma in the upper urinary tract. 3-6). Overall, of 16 reported PC system lesions on CTU, 12 (75%) proved to be tumors, and of 11 reported ureteric lesions, 6 (55%) proved to be tumors. Fluoro intermittently to monitor opacification of renal pelvis/calyces, ureter, and bladder. An award-winning, radiologic teaching site for medical students and those starting out in radiology focusing on chest, GI, cardiac and musculoskeletal diseases containing hundreds of lectures, quizzes, hand-out notes, interactive material, most commons lists and pictorial differential diagnoses Türk C, Neisius A, Petrik A, et al. . Figure 1. Excretory phase CT urography for opacification of the urinary collecting system. 4.4.4.4. The renal collecting system is divided into 4 segments; renal calyces and infundibula (CI), renal pelvis (RP), upper ureter above the level of the iliac crest (UP), and lower ureter below the iliac crest (LU). It is timed such that urine opacifies with contrast and allows for greater contrast separation between urine and soft-tissue density, which appear as filling defects. Renal cortical defects have a variety of causes, and present on imaging as an area of focal cortical thinning or absence of renal cortex, sometimes accompanied by focal caliectasis. Antopol-Goldman (AG) lesion is a benign condition characterized by flank pain, hematuria, and radiologically detected filling defect in the renal pelvis. The delayed phase on a subsequent computed tomography (CT) abdomen and pelvis showed a filling defect in the left renal pelvicalyceal system, suspicious for a transitional cell carcinoma. Urothelial carcinoma affects more than 70,000 Americans annually [].Although the incidence of urothelial tumors in the upper urinary collecting system may be low in the general population (one or two cases per 100,000 people annually), the incidence increases in patients with prior or concurrent urothelial tumors in the lower urinary tract, with a reported incidence of 3.9-4.8% [2-4]. Decreasing shadow (filling defect) of collecting system, mammary duct, uterus and uterine tube cavities. Hydronephrosis is the most common congenital abnormality detected by antenatal ultrasound. Ultrasound alone is insufficient for imaging of hematuria. fect ( fil'ing dē'fekt) Displacement of contrast medium by a space-occupying lesion in a radiographic study of a contrast-filled hollow viscus, such as a polyp on a barium enema; also applied to defects in the otherwise uniform distribution of radionuclide in an organ, such as a metastasis in the liver on a 99mTc-sulfur colloid scan. (preoperative urinary cytology, filling defect and PNV) was done using McNemar's test. No other renal tract calcification was identified. demonstrated a radiolucent filling defect in the distal left ureter . Türk C, Neisius A, Petrik A, et al. Since imaging features of urinary system metastases cannot exclude the possibility of a primary tumor of the urinary system, histopathologic examination of renal masses in patients with an extra-urinary malignancy is necessary in the management of and the decisions regarding the treatment options of these patients (3, 7, 10, 40). Case 1: 69 year old man with transitional cell carcinoma of the right renal pelvis, which can be visualized on the corticumedullary phase (A) as enhancing soft tissue against urine in the renal pelvis, or on the delayed phase (B) as a filling defect in the opacified collecting system. RPC 1 of the Month from the AFIF 2 Cdr Elias G. Theros , MC USN Registry of Radiologic Pathology, Armed Forces Institute of Pathology, Washington, D. C. 20305 Excerpt T HE RADIOGRAPHIC findings in this intravenous urogram of a 50-yearoldman: Represent multiple foci of a transitional- cell carcinoma of the kidney pelvis and ureter Represent the "beaded" appearance typical of long-standing . 1 x. Pre-contrast CT of the abdomen and pelvis in axial and coronal planes reveal the presence of right staghorn calculi occupying the renal pelvis and various calyces, with fragmentation, and the bigger fragment with 20mm, and a renal stone in the left kidney. o If using gravity drip, open vent on tubing adjacent to bottle. . CTU was performed on 89 sloughed papillae cause filling defects in collecting system: "ring sign." • Tissue necrosis leads to blunted or clubbedcalyces. It can help to define the level of urinary tract obstruction. It was initially described as a sign of duplication of the collecting system 1 (a slice obtained between the two collecting systems will not demonstrate the normal components o. There are three free luminal filling defects present within the urinary bladder including: air bubbles, calculi, and blood clots. It is clinically important because it is confused with renal parenchymal and collecting system tumors. The collecting system may be better imaged with direct contrast injection than with excretory urography, particularly in cases of high-grade urinary obstruction (Fig. distend the collecting system and ureter. Radiology 92:1447-1452, 1969. The purpose of the study was to evaluate and compare opacification of the renal collecting system and ureters detected by computed tomographic urography (CTU) performed 20 min and 1 h after the ingestion of 1,000 ml of water. Renal matrix stones are a rare phenomenon and they present a diagnostic challenge due to their atypical radiological appearances in comparison to more commonly encountered renal tract calculi. Multiple filling defects within a ureter, as seen on conventional IVU or CT IVU, have a relatively small differential including: spreading or multifocal transitional cell carcinoma (TCC) vascular indentations multiple ureteral stones (steinstr. It can help to define the level of urinary tract obstruction. However, it is useful when the renal collecting system opacifies poorly with intravenous contrast or when there is renal insufficiency. 1 Since then radionuclide renal imaging in pediatrics has been one of the cornerstones in pediatric nuclear medicine. Both upper . X-rays, or plain films / plain radiographs, are used as a first-line imaging investigation in most situations due to their low radiation dose and easy availability. heterogeneous calculi filling renal pelvis with low Hounsfield units (+120HU), which was very atypical for a calculus on CT imaging. Filling defect of ureter found on diagnostic imaging. 9. No sonographic features are specific for TCC, and many filling defects within the renal collecting system and bladder have a nonspecific appearance. 21.10). There is also a calyceal diverticulum in the inferior calyceal group of the right . Fig. A urothelial neoplasm involving the renal calyces may be seen as a subtle enhancing mass at early postcontrast CT and as a filling defect within the calyces in the excretory phase. o If hand injecting, use gentle pressure. . Post contrast imaging showed multiple irregular filling defects within the calyces of both kidneys (Fig. Poor visualization of renal collecting system in intravenous urography as an indicator of invasive transitional cell carcinoma in the upper urinary tract. Renal hypertension Ureterocele. of 12 • Fill upper tract collecting system with contrast. A faceless kidney refers to one in which the normal appearance of the renal sinus on cross-sectional imaging is absent. fat-containing renal mass filling defect in renal collecting system fluid collection in scrotum focal bladder wall thickening focal calcification in kidney focal defect in nephrogram focal renal parenchymal scar free fluid in cul-de-sac >> Return to top. Abnormal radiologic findings on diagnostic imaging of other urinary organs. The classical features of UTUC on CT imaging are tumour located centrally in the collecting system, focal-filling defect in renal pelvis, renal shape preservation, absence of cystic or necrotic . Unclamp PCN of interest. Short description: Abn radlgc find on dx imaging renal pelv, ureter, or blddr The 2022 edition of ICD-10-CM R93.41 became effective on October 1, 2021. Filling defect of bladder found on diagnostic imaging. Overview of imaging modalities. and MRI are other imaging techniques that are used for evaluation of the urinary tract. The patient underwent ureteroscopic biopsy suggestive of a papillary neoplasia, before progressing to a laparoscopic radical . . 2 [99m Tc]Tc-mercaptoacetyltriglycine ([99m Tc]Tc-MAG3) renography has proven to be a valuable tool guiding clinical . urinary organs, specified NEC R93.49. Small subepithelial inflammatory cysts in the renal pelvis and/or ureter characterize pyeloureteritis and ureteritis cystica, respectively.The cysts appear as multiple smooth filling defects most commonly in the proximal one-third of the ureter and are often seen in association with chronic urinary tract infections or stones. Ultrasound alone is insufficient for imaging of hematuria. . Nuclear imaging measures the uptake of various labelled radioactive isotopes. Radioisotope renography was first described in 1956. On the 'aft the kidney is small with opacification of calyces which seem to drain only the lower pole. 6,10(pp191-192),11 . Urothelial tumors are multifocal in 10-20% of cases and, therefore, should be high on the differential diag . Small stones within the urinary collecting system will appear as filling defects on postcontrast images and may simulate a UC. Materials and methods: We conducted a retrospective study to evaluate 326 . There was a 5 mm soft tissue mass in the distal left ureter (Fig. Dilatation of the upper pole and mid renal calyces are observed. Excretory urogram shows a large right kidney w ith a duplicated collecting system. This is the American ICD-10-CM version of R93.41 - other international versions of ICD-10 R93.41 may differ. . No dye is injected during the procedure. There are three free luminal filling defects present within the urinary bladder including: air bubbles, calculi, and blood clots. Poor visualization of renal collecting system in intravenous urography as an indicator of invasive transitional cell carcinoma in the upper urinary tract. Imaging characteristics associated with failure of nonoperative management in high-grade pediatric blunt renal trauma. Objective: The purpose of this article is to assess the ability of CT urography to depict urothelial tumors in the upper renal collecting systems, compared with ureteroscopy and pathologic analysis, and to describe the relative implication of the radiologic signs of urothelial thickening and endoluminal filling defects. Urinary tract imaging and pathology . Antibiotics prophylaxis is needed prior to this imaging. Overview of imaging modalities. CT urogram utilizing a split dose technique: Axial image through the kidneys and collecting systems demonstrates both nephrographic and excretory phases of enhancement in the same imaging sequence. This potentially embarrassing misinterpretation can be avoided by always correlating the abnormal filling defect with the unenhanced images to be sure it is not, in fact, a stone. Axial CT with contrast of the abdomen shows the mass to almost complete fill the base of the bladder. 4 Diuretic renography can be helpful in these clinical scenarios. Using ultrasound alone, it is often difficult to differentiate renal transitional cell carcinoma from other causes of filling defects of the renal collecting system such as blood clots, sloughed papillae, or fungus balls. size and location of primary tumor, extension into pubic bone; spread to adjacent tissues or organs; regional lymph nodes; sites of distant organs or lymph nodes involved.. KUB (Kidneys-Ureters-Bladder) X-rays to evaluate the status of the urinary system. 6). sloughed papillae cause filling defects in collecting system: "ring sign." • Tissue necrosis leads to blunted or clubbedcalyces. 10. . Pyeloureteritis cystica is characterized on imaging by multiple small (2-5 mm), round, smooth-walled, eccentric filling defects protruding from the wall of the renal pelvis or ureter (Fig. We tracked immediate complications and tract seeding on follow-up imaging the & # x27 ; the... 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